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Chapter 1: Burden of Digestive Disorders
When accounting for population growth and ageing, age-standardised incidence rates have
increased only slightly by around 1%, from 6035 per 100,000 in 2000, to 6104 per 100,000 in
2019, for the member countries combined (Figure 1). Whilst the total number of deaths due
to digestive diseases have increased over time, age-standardised mortality rates have
decreased by around 12% from 36 per 100,000 in 2000, to 32 per 100,000 in 2019, which
likely reflects improved survival of patients with digestive diseases. Stable incidence and
better survival have thus resulted in an increase in the prevalence of digestive diseases over
time. Age-standardised prevalence rates have increased by around 5%, from 26,803 per
100,000 in 2000, to 28,124 per 100,000 in 2019, for the member countries combined.
Figure 1.
Numbers and age−standardised incidence , death and prevalence rates for digestive diseases for 44
UEG member countries combined, 2000−2019
Incidence
Deaths
20,000,000
40,000,000
60,000,000
2000
2005
2010
Year
Prevalence
30,000
100,000,000
200,000,000
300,000,000
2000
2005
2010
Year
2015
20,000
10,000
2020
2015
2,000
4,000
6,000
2020
100,000
200,000
300,000
400,000
500,000
2000
2005
2010
Year
Source: authors' compilation using GBD 2019 data
2015
10
20
30
40
2020
A DALY is a measure which combines years of life lost due to premature mortality and years
of healthy life lost due to disability. Amongst the member countries, age-standardised DALY
rates for digestive diseases range from 427 to 2858 per 100,000 (Figure 2). Age-standardised
DALY rates tend to be higher amongst member countries located towards the east of Europe.
Age-standardised DALY rates are highest within Egypt. Out of the 44 countries, 6 (14%) have
experienced a percentage change increase in age-standardised DALY rates from 2000-2019,
including some countries within Western Asia and Central and Eastern Europe. Member
countries within all other regions have experienced decreases in age-standardised DALY rates
since 2000.
White Book 2: Part 1
4
Age−standardised rate per 100,000
Age−standardised rate per 100,000
Age−standardised rate per 100,000
Number of prevalent cases
Number of incident cases
Number of deaths

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